In Vitro Antioxidant and Ex Vivo Anticataract Activity of Hydroalcoholic Extract of Cordia obliqua Willd

Cordia obliqua has a long history of use in the treatment cataract and other eye-related problems Indian traditional medicine. High oxidative stress is one major underlying causes which results precipitation natural protein present lenses with aging. This research been carried out to determine anti-cataract activity by performing various antioxidant techniques such as 1,1-diphenyl-2-picrylhydrazyl, hydrogen peroxide, ABTS radical cation Ferric reducing potential studies stress–induced ex vivo model. Results study conducted hydroalcoholic extract leaves revealed presence phytoconstituents alkaloids, phenols, flavonoids, etc. Total phenol total flavonoid content was found be 53 ± 3.21and 26.12 2.54% respectively, that plant contains good amount these compounds hence possesses activity. Furthermore, IC50 values obtained from all methods gave strong evidence regarding this plant. Anti-cataract also investigated using goat eye promising were speak voluminously about its support well-prescribed use. clearly supported significant anticataract Further, demands great attention for development suitable novel dosage forms effective cataract.
 Keywords: obliqua, cataract,